Back to results
US 10,953,087 B2Granted
Stabilized pre-fusion RSV F proteins
AssigneeJanssen Vaccines & Prevention B.V.
InventorJohannes Petrus Maria Langedijk
Life of this patent
Estimating the term…
Abstract
Stable pre-fusion respiratory syncitial virus (RSV) F proteins, immunogenic compositions including the proteins and uses thereof for the prevention and/or treatment of RSV infection are described.
Claims32
A recombinant pre-fusion respiratory syncytial virus (RSV) Fusion (F) protein comprising a mutation of the amino acid residue at position 215, a mutation of the amino acid residue at position 357, and a mutation of the amino acid residue at position 371, wherein the amino acid positions correspond to the numbering of the amino acid sequence of SEQ ID NO:
- 13.
Dependencies are inferred from the claim text.