Marking tissue surfaces for treatment of lesions by electrical nanopulses
AssigneePuise Biosciences, Inc.
InventorsCesar Escobar Blanco, Elena Tovkan Forster, Stefani Reiko Takahashi
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Abstract
This disclosure relates to an in vivo treatment of tissue, for example, a skin lesion of a mammal comprising application of electrical energy to the skin lesion in a form of electrical pulses. At least one electrical pulse is applied. The pulse duration may be at least 1 nanosecond. Surface of a tissue surrounding the skin lesion may be marked to guide the device to deliver the electric pulses at substantially precise locations on the lesion surface. This treatment may prevent at least growth of the lesion.
Claims30
A method for positioning a pulse delivery device, the method comprising:
- transferring a film comprising a device guiding mark from a decal to a region on a surface of an object such that the film and the device guiding mark detachably attach to the object surface;
- and
- after the film is transferred to the region on the object surface, passing a distal end of at least one delivery electrode of the pulse delivery device through the film at the device guiding mark to be in contact with the region on the object surface.
A method for positioning a pulse delivery device, the method comprising:
- transferring a film of a decal to a region on a surface of an object, the film comprising at least one device guiding mark and a marked area configured to indicate a boundary around the region, such that the film, the marked area and the at least one device guiding mark detachably attach to the object surface;
- and
- after transferring the film, aligning an applicator tip of the pulse delivery device with the at least one device guiding mark such that a distal end of at least one delivery electrode of the pulse delivery device is positioned inside an area defined by the marked area when the applicator tip is brought in contact with the region on the object surface,
- wherein the region has a size corresponding to a treatment zone.
A method for positioning an applicator tip of a pulse delivery device, the method comprising:
- transferring a film comprising at least one device guiding mark from a decal to a surface of an object such that the film and the device guiding mark detachably attach to the object surface;
- after the film is transferred to the object surface, using at least one device alignment line on the applicator tip and the device guiding mark of the film to orient the applicator tip and position a distal end of at least one delivery electrode of the applicator tip in relation to a region on the object surface.
Dependencies are inferred from the claim text.