Imaging mass spectrometry data processing device and imaging mass spectrometry data processing method
AssigneeShimadzu Corporation
InventorsMasahiro Ikegami, Koretsugu Ogata
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AssigneeShimadzu Corporation
InventorsMasahiro Ikegami, Koretsugu Ogata
Estimating the term…
The user specifies regions of interest (ROIs) such as a region where a large amount of compound to be identified is estimated to be included and a region where the compound is overlapped with another compound on one or more specific MS images, and specifies addition or subtraction of the ROIs. For each of the specified ROIs, an average MS/MS spectrum is calculated from MS/MS spectrum data at measurement points in the regions, and the average MS/MS spectra at the ROIs are subjected to addition or subtraction, to obtain an MS/MS spectrum. By addition between the ROIs, the intensity of peak derived from the target compound can be increased. By subtraction between the ROIs, a peak derived from the other compound overlapped with the target compound can be removed. When the MS/MS spectrum after addition or subtraction is subjected to library search for identification, a score indicating the similarity of the spectrum is higher than the conventional score, and the identification accuracy can be improved.
An imaging mass spectrometry data processing device for processing MSn spectrum data obtained by MSn analysis (n is an integer of two or more) at each of a plurality of measurement points within a predetermined region to be measured on a sample, comprising:
An imaging mass spectrometry data processing method for processing MSn spectrum data obtained by MSn analysis (n is an integer of two or more) at each of a plurality of measurement points within a predetermined region to be measured on a sample, comprising:
Dependencies are inferred from the claim text.