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US 10,948,362 B2Granted
Predicting temperature response
AssigneeNew York University
InventorsGiuseppe Carluccio, Christopher M. Collins
Life of this patent
Estimating the term…
Abstract
After the temperature response to a single period of heating (SAR segment) is determined, temperature increases for an arbitrary timecourse of heating is determined based upon a convolution of the temperature response curve for a sequence of different SAR segments.
Claims9
A method of predicting temperature increase for a material comprising:
- applying a radio frequency dosage to a tissue;
- determining, for an initial SAR segment having a first radio frequency dosage, an initial temperature response of the tissue (T0(t)) at an initial amplitude (c0) and initial duration (Δ);
- predicting a change in temperature of the tissue for an arbitrary sequence of SAR segments where the temperature response to a single segment is known;
- wherein the temperature change is estimated using the equation
- T
- n
-
- (
- t
- )
- =
- ∑
- n
- =
- 1
- N
-
-
- c
- n
- c
- 0
-
- T
- 0
-
- (
- t
- -
- n
-
-
- Δ
-
-
- t
- )
- where cn is the amplitude of the nth SAR segment applied, t is time, Tn(t) is the temperature after the nth SAR segment, and T0(t) is the initial temperature response to the initial SAR segment with amplitude of c0 and duration Δt;
- altering the radio frequency dosage to the tissue to a second radio frequency dosage;
- and
- calculating a new temperature of the tissue based on the predicted temperature change equation and the second radio frequency dosage.
38 more elements
A computer-implemented machine for measuring long-term temperature increase for a tissue comprising:
- a MRI machine having a coil;
- a processor in communication with the MRI machine;
- and
- a tangible computer-readable medium operatively connected to the processor and including computer code configured for:
- applying, via the coil, a first radio frequency dosage to a tissue for an initial SAR segment;
- determining, for an initial SAR segment, an initial temperature response (T0(t)) at an initial amplitude (c0) and initial duration (Δ);
- determining a temperature increase prediction for a tissue or material wherein a change in temperature is estimated using the equation
- T
- n
-
- (
- t
- )
- =
- ∑
- n
- =
- 1
- N
-
-
- c
- n
- c
- 0
-
- T
- 0
-
- (
- t
- -
- n
-
-
- Δ
-
-
- t
- )
- where cn is the amplitude of the nth SAR segment applied, t is time, Tn(t) is the temperature after the nth SAR segment, and T0(t) is the temperature response to a SAR segment with amplitude of c0 and duration Δt;
- and
- predicting a second SAR segment temperature change of the tissue for a second SAR segment having a second radio frequency dosage, wherein the prediction is based upon the change in temperature estimate.
40 more elements
Dependencies are inferred from the claim text.