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US 10,947,513 B2Granted
Engineered virus
AssigneeReplimune Limited
InventorRobert Coffin
Life of this patent
Estimating the term…
Abstract
The present invention relates to oncolytic virus comprising: (i) a GM-CSF-encoding gene; and (ii) an immune co-stimulatory pathway activating molecule or an immune co-stimulatory pathway activating molecule-encoding gene.
Claims26
An oncolytic virus comprising:
- (i) a heterologous GM-CSF-encoding gene;
- and (ii) a heterologous CTLA-4 inhibitor encoding gene, wherein both heterologous genes are inserted into the genome of the virus.
Dependencies are inferred from the claim text.