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US 10,947,229 B2Granted
Dimethyl amino azetidine amides as JAK inhibitors
AssigneeTheravance Biopharma R&D IP, LLC
InventorsDaniel D. Long, Cameron Smith, Corbin Thompson
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Abstract
The invention provides compounds of formula (I): where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds and methods of using such compounds to treat respiratory diseases.
Claims15
A compound of formula (I):
- or a pharmaceutically-acceptable salt thereof
- wherein:
- n is 0, 1 or 2;
- R1 is C1-3 alkyl;
- and
- each R2 is independently C1-3 alkyl.
3 more elements
A compound of formula 1:
- or a pharmaceutically-acceptable salt thereof.
A compound of formula 1:
Dependencies are inferred from the claim text.