GP130 modulators
AssigneeThe Regents of the University of California
InventorsMohammad Parvez Alam, Varghese John, Patricia Spilman, Kanagasabai Vadivel
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Abstract
There are provided, inter alia, compounds and methods useful for the treatment of neurological conditions, such as neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.
Claims17
A method for treating Alzheimer's disease in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound or a pharmaceutically acceptable salt thereof;
- wherein the compound is:
A method for treating Alzheimer's disease in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound or a pharmaceutically acceptable salt thereof;
- wherein the compound is:
A method for treating Alzheimer's disease in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of Formula (A) or a pharmaceutically acceptable salt thereof;
- wherein the compound of Formula (A) is:
- wherein:
- X1 is oxygen or sulfur;
- X6 and X9 are each independently CH or N;
- R4 is halogen;
- and
- z1 is an integer from 0 to 5.
Dependencies are inferred from the claim text.