Cationic lipid
AssigneeEisai R&D Management Co., Ltd.
InventorsYuta Suzuki, Yoshinori Takahashi
Life of this patent
Estimating the term…
Abstract
The present invention provides a cationic lipid which is able to be used for nucleic acid delivery to the cytoplasm. A cationic lipid according to the present invention is, for example, a compound represented by formula (1) or a pharmaceutically acceptable salt thereof, wherein L1 and L2 independently represent an alkylene group having 3 to 10 carbon atoms; R1 and R2 independently represent an alkyl group having 4 to 24 carbon atoms or an alkenyl group having 4 to 24 carbon atoms; R3 represents an alkyl group having 1 to 3 carbon atoms; and X1 represents a single bond or CO—O—.
Claims14
A compound represented by formula (1) or a pharmaceutically acceptable salt thereof:
- wherein L1 and L2 independently represent an alkylene group having 3 to 10 carbon atoms;
- R1 and R2 independently represent an alkyl group having 4 to 24 carbon atoms or an alkenyl group having 4 to 24 carbon atoms;
- R3 represents an alkyl group having 1 to 3 carbon atoms;
- and X1 represents a single bond or CO—O—.
Dependencies are inferred from the claim text.