Crystal form of dezocine and preparation method therefor
AssigneeYangtze River Pharmaceutical Group Co., Ltd.
InventorsJingren Xu, Wei Cai, Haoyu Xu, Ying Xu, Zhichao Xiao, Shiwei Yao
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Abstract
Disclosed is a crystal form of dezocine. The X-ray powder diffraction (XRD) pattern thereof is determined using Cu/K-α1 and has diffraction peaks at the 2θ value of 9.1±0.2 and 12.2±0.2, with the height % of these diffraction peaks greater than 20. Also disclosed are a preparation method for the crystal form, a pharmaceutical composition and use thereof. The crystal form of dezocine has good solubility, the preparation method has simple operations, good reproducibility, suitability for industrial production and the like.
Claims16
A crystal form of dezocine, wherein the X-ray powder diffraction (XRD) pattern of the crystal form of dezocine is determined using Cu/K-al and has diffraction peaks at 2θ value of 9.1±0.2, 12.2±0.2, 13.0±0.2, 13.6±0.2, 14.0±0.2, 14.7±0.2, 15.2±0.2, 19.6±0.2, 23.1±0.2, 24.4.4±0.2, and 27.2±0.2, with the height % of the diffraction peaks greater than 20.
Dependencies are inferred from the claim text.