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US 10,947,033 B2Granted
Reduction in stress cracking of films
AssigneeAquestive Therapeutics, Inc.
InventorsBeuford Arlie Bogue, Greg Slominski
Life of this patent
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Abstract
Methods and packages for storing film strips while reducing or eliminating stress cracking during storage, including use of packages having an inner surface made from polymeric materials exhibiting various physical properties and including films and pouches that are annealed.
Claims20
A method for reducing or preventing stress-cracking in a film product, comprising:
- (1) providing a package for storing an active-containing film product, said package comprising:
- (a) a top layer having an inner surface and an outer surface;
- and
- (b) a bottom layer having an inner surface and an outer surface,
- wherein said inner surface of said bottom layer comprises at least one polymeric material having at least one physical characteristic selected from the group consisting of:
- (i) a surface energy as measured by a water contact angle test of about 100 degrees or greater;
- and
- (ii) a surface RMS roughness of less than about 800 nm as measured by atomic force microscopy at a 100 micron square sample size level;
- wherein said polymeric material has a surface adhesivity level of less than about 0.25 lbf as measured by a peel force test using a load frame and packaging tape;
- and
- (2) packaging a film product comprising an active within said package;
- wherein stress-cracking of said film product is prevented or reduced when said film product is packaged in said package.
9 more elements
Dependencies are inferred from the claim text.