Microtome blade and/or microtome blade holder cleaning using adhesive material
AssigneeAgilent Technologies, Inc.
InventorsKyle Schleifer, Carol T Schembri, Young-Ping Hwung
Life of this patent
Estimating the term…
Abstract
The present disclosure related to apparatus and methods for removing waste of debris from a microtome blade, a microtome blade holder, or both. The invention also relates to automated systems and methods for cleaning a microtome.
Claims24
A method for cleaning a microtome blade, a microtome blade holder, or both, the method comprising:
- collecting debris from at least one of the microtome blade, or the blade holder, on an adhesive material, wherein the debris comprises one or more component selected from the group consisting of embedding medium, paraffin, tissue, and genomic material;
- and
- removing the adhesive material and the collected debris.
A method of collecting and transferring a tissue section sliced by a microtome, the method comprising:
- collecting a tissue section sliced from a tissue sample on an adhesive material, wherein the adhesive material has an identifier;
- and
- removing the adhesive material and the collected tissue section from the microtome.
An apparatus for slicing a tissue section from a sample, comprising:
- a microtome comprising a sample holder, a microtome blade holder and a microtome blade held by the microtome blade holder opposite the sample holder, such that when the sample holder is moved linearly, a sample held by the sample holder is sliced by the microtome blade to form a tissue section;
- a debris collector capable of at least one of rotational motion, or linear motion, wherein the debris collector comprises or is adapted for holding an adhesive material.
A method for cleaning a microtome blade, a microtome blade holder, or both, the method comprising:
- cleaning at least one of the microtome blade, or the microtome blade holder, with a liquid-holding medium removably attached to a collector comprising an extendible arm adapted to move the liquid holding medium into contact with at least one of the microtome blade, or the microtome blade holder.
Dependencies are inferred from the claim text.