# US 10,946,212 B2 · Implantable device for optical stimulation of the brain

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- Number: US 10,946,212 B2
- Document ID: US10946212B2
- Status: Granted
- Kind: B2
- Application number: 16/063,258
- Filed: 2016-12-07
- Published: 2019-01-03
- Granted: 2021-03-16
- Earliest claimed: 2015-12-17
- Assignees: Commissariat A L'energie Atomique Et Aux Energies Alternatives
- Applicants: Commissariat à I'Energie Atomique et aux Energies Alternatives
- Inventors: Claude Chabrol; Alim-Louis Benabid
- Web page: https://patentgrep.com/patent/US10946212B2

## CPC

- A61N 5/0622: {Optical stimulation for exciting neural tissue}
- A61B 5/293: Invasive
- A61N 5/0601: {Apparatus for use inside the body}
- A61N 2005/063: {comprising light transmitting means, e.g. optical fibres}
- A61N 2005/0651: {Diodes}
- A61N 2005/0659: {infrared}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

The invention relates to an implantable device for optical stimulation of an organ of the human or animal body, having a probe comprising a tube made of a first transparent material, this tube being hermetically closed by at least one stopper; at least one light source arranged inside the tube; a plurality of electrical connection elements extending through the stopper and electrically connecting said at least one light source to the outside of the tube; and a linking cable arranged outside the tube and connected to said connection elements.

## Claims

### Claim 1

An implantable device for optical stimulation of an organ of a human or animal body, comprising a probe comprising:
a tube made of a first transparent material, the tube being hermetically closed by at least one cap;
at least one light source arranged inside of the tube;
a plurality of electric connection elements running through the at least one cap and electrically coupling said at least one light source outside of the tube;
a connecting cable arranged outside of the tube, connected to said connection elements;
a sensor configured for detecting a possible leakage in the tube, the sensor comprising an organic light-emitting diode located inside the tube; and
a sheath made of a second transparent material coating the tube and the cable.

### Claim 2 (depends on 1)

The device of claim 1, wherein the second material is an elastomeric material.

### Claim 3 (depends on 1)

The device of claim 1, wherein the first material is sapphire or silica.

### Claim 4 (depends on 1)

The device of claim 1, wherein the probe has an elongated shape, the tube being located at a first end of the probe and the connecting cable coupling the at least one light source to a second end of the probe opposite to the first end.

### Claim 5 (depends on 1)

The device of claim 1, further comprising a power supply and control unit electrically coupled to the at least one light source via the connecting cable.

### Claim 6 (depends on 1)

The device of claim 1, wherein the light source comprises one or a plurality of light-emitting diodes.

### Claim 7 (depends on 1)

The device of claim 1, wherein said sensor further comprises a circuit for measuring a quantity representative of impedance of the organic light-emitting diode and/or of light efficiency of the organic light-emitting diode.

### Claim 8 (depends on 1)

The device of claim 1, wherein a transparent filling material is arranged inside of the tube.

### Claim 9 (depends on 1)

The device of claim 1, wherein the probe further comprises electrodes capable of implementing an electric stimulation of an organ of the human or animal body.