# US 10,946,201 B2 · Point-and-click programming for deep brain stimulation using real-time monopolar review trendlines

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- Number: US 10,946,201 B2
- Document ID: US10946201B2
- Status: Granted
- Kind: B2
- Application number: 16/284,917
- Filed: 2019-02-25
- Published: 2019-06-20
- Granted: 2021-03-16
- Earliest claimed: 2012-08-28
- Assignees: Boston Scientific Neuromodulation Corporation
- Applicants: Boston Scientific Neuromodulation Corporation
- Inventors: Stephen Carcieri; Dean Chen; Michael A. Moffitt
- Web page: https://patentgrep.com/patent/US10946201B2

## CPC

- A61N 1/37247: {User interfaces, e.g. input or presentation means}
- A61N 1/0534: {Electrodes for deep brain stimulation}
- A61N 1/3605: {Implantable neurostimulators for stimulating central or peripheral nerve system}
- A61N 1/36185: {Selection of the electrode configuration}
- A61N 1/372: Arrangements in connection with the implantation of stimulators
- G16H 40/63: for local operation
- G16Z 99/00: Subject matter not provided for in other main groups of this subclass
- A61N 1/36082: {Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16Z: INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR

## Abstract

A system and method for selecting leadwire stimulation parameters includes a processor iteratively performing, for each of a plurality of values for a particular stimulation parameter, each value corresponding to a respective current field: (a) shifting the current field longitudinally and/or rotationally to a respective plurality of locations about the leadwire; and (b) for each of the respective plurality of locations, obtaining clinical effect information regarding a respective stimulation of the patient tissue produced by the respective current field at the respective location; and displaying a graph plotting the clinical effect information against values for the particular stimulation parameter and locations about the leadwire, and/or based on the obtained clinical effect information, identifying an optimal combination of a selected value for the particular stimulation parameter and selected location about the leadwire at which to perform a stimulation using the selected value.

## Claims

### Claim 1

A system for facilitating a selection of electrical stimulation parameters for stimulating patient tissue, the system comprising:
a display; and
a computer processor configured for:
displaying, on the display, a plurality of two-dimensional graphs arranged at different longitudinal levels along an axis corresponding to an axis of a leadwire, each of the two-dimensional graphs corresponds to stimulation at the corresponding longitudinal level;
receiving a user selection of a point on one of the two-dimensional graphs, wherein the point corresponds to a first value of a particular stimulation parameter and a first location on the leadwire; and
initiating a signal to program an implantable pulse generator with the first value of the particular stimulation parameter and a selection of one or more electrodes on the leadwire corresponding to the first location on the leadwire to produce a stimulation.

### Claim 2 (depends on 1)

The system of claim 1, wherein at least one of the two-dimensional graphs comprises a first shape representing estimated therapeutic minimum amplitude values.

### Claim 3 (depends on 2)

The system of claim 2, wherein at least one of the two-dimensional graphs further comprises a second shape representing estimated maximum amplitude values above which a side effect is estimated to occur.

### Claim 4 (depends on 3)

The system of claim 3, wherein the computer processor is further configured for graphically identifying by distinguishable indicia a region of within the second shape that lies outside the first shape to indicate an estimated region of suitable stimulation parameters.

### Claim 5 (depends on 1)

The system of claim 1, wherein at least one of the two-dimensional graphs comprises a shape representing estimated maximum amplitude values above which a side effect is estimated to occur.

### Claim 6 (depends on 1)

The system of claim 1, wherein the computer processor is further configured for displaying a model of the leadwire and electrodes of the leadwire.

### Claim 7 (depends on 6)

The system of claim 6, wherein the plurality of two-dimensional graphs are overlaid on the model of the leadwire.

### Claim 8 (depends on 1)

The system of claim 1, wherein the computer processor is further configured for displaying one or more view rotation controls and, in response to actuation of one of the view rotation controls, rotating the two-dimensional graphs about the axis.

### Claim 9

A method for facilitating a selection of electrical stimulation parameters, the method comprising:
displaying a plurality of two-dimensional graphs arranged at different longitudinal levels along an axis corresponding to an axis of a leadwire, each of the two-dimensional graphs corresponds to stimulation at the corresponding longitudinal level;
receiving a user selection of a point on one of the two-dimensional graphs, wherein the point corresponds to a first value of a particular stimulation parameter and a first location on the leadwire; and
initiating a signal to program an implantable pulse generator with the first value of the particular stimulation parameter and a selection of one or more electrodes on the leadwire corresponding to the first location on the leadwire to produce a stimulation.

### Claim 10 (depends on 9)

The method of claim 9, wherein at least one of the two-dimensional graphs comprises a first shape representing estimated therapeutic minimum amplitude values.

### Claim 11 (depends on 9)

The method of claim 9, wherein at least one of the two-dimensional graphs further comprises a second shape representing estimated maximum amplitude values above which a side effect is estimated to occur.

### Claim 12 (depends on 11)

The method of claim 11, further comprising graphically identifying by distinguishable indicia a region of within the second shape that lies outside the first shape to indicate an estimated region of suitable stimulation parameters.

### Claim 13 (depends on 9)

The method of claim 9, wherein at least one of the two-dimensional graphs comprises a shape representing estimated maximum amplitude values above which a side effect is estimated to occur.

### Claim 14 (depends on 9)

The method of claim 9, further comprising displaying a model of the leadwire and electrodes of the leadwire.

### Claim 15 (depends on 14)

The method of claim 14, wherein the plurality of two-dimensional graphs are overlaid on the model of the leadwire.

### Claim 16 (depends on 9)

The method of claim 9, further comprising displaying one or more view rotation controls and, in response to actuation of one of the view rotation controls, rotating the two-dimensional graphs about the axis.

### Claim 17

A non-transitory computer-readable medium containing instructions to perform a method for facilitating a selection of electrical stimulation parameters for stimulating patient tissue, the method comprising:
displaying, on a display, a plurality of two-dimensional graphs arranged at different longitudinal levels along an axis corresponding to an axis of a leadwire, each of the two-dimensional graphs corresponds to stimulation at the corresponding longitudinal level;
receiving a user selection of a point on one of the two-dimensional graphs, wherein the point corresponds to a first value of a particular stimulation parameter and a first location on the leadwire; and
initiating a signal to program an implantable pulse generator with the first value of the particular stimulation parameter and a selection of one or more electrodes on the leadwire corresponding to the first location on the leadwire to produce a stimulation.

### Claim 18 (depends on 17)

The non-transitory computer-readable medium of claim 17, wherein at least one of the two-dimensional graphs comprises a first shape representing estimated therapeutic minimum amplitude values.

### Claim 19 (depends on 17)

The non-transitory computer-readable medium of claim 17, wherein at least one of the two-dimensional graphs further comprises a second shape representing estimated maximum amplitude values above which a side effect is estimated to occur.

### Claim 20 (depends on 17)

The non-transitory computer-readable medium of claim 17, wherein the method further comprises displaying one or more view rotation controls and, in response to actuation of one of the view rotation controls, rotating the two-dimensional graphs about the axis.
