# US 10,946,145 B2 · Device for intraocular fluid injection > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,946,145 B2 - Document ID: US10946145B2 - Status: Granted - Kind: B2 - Application number: 16/706,538 - Filed: 2019-12-06 - Published: 2020-04-09 - Granted: 2021-03-16 - Earliest claimed: 2018-04-12 - Assignees: New World Medical, Inc. - Applicants: New World Medical, Inc. - Inventors: Vijay R. Balan; Nico J. Slabber - Web page: https://patentgrep.com/patent/US10946145B2 ## CPC - A61F 9/00736: {Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments (A61F9/008 takes precedence)} - A61M 5/31563: {interacting with a displaceable stop member} - A61B 17/3211: Surgical scalpels, knives; Accessories therefor - A61M 5/31581: {the component being manually operated or triggered by a rotating or pivoting actuator operated by user, e.g. an injection lever or handle} - A61M 5/31585: {the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button} - A61F 9/0008: {Introducing ophthalmic products into the ocular cavity or retaining products therein (putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00)} - A61M 2005/3114: {Filling or refilling} - A61M 2210/0612: Eyes - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Devices and methods for intraocular fluid injection are disclosed. A device can include a surgical instrument for an ophthalmic procedure. The surgical instrument can include a handle. A fluid compartment can be coupled to the handle and configured to hold a substance. A tool can be coupled to the distal end of the handle and have a lumen configured to convey the substance into an intraocular site of a patient. A piston can be in the handle and configured to reciprocate along the longitudinal axis of the handle to draw the substance from the fluid compartment and eject the substance through the lumen of the tool. A push button can be on the lateral side of the housing and configured to engage the piston via a sloped surface to actuate a forward stroke of the piston towards the distal end of the handle. ## Claims ### Claim 1 A medical instrument, comprising: an elongate tubular housing having a distal end and a proximal end; a tool section coupled to the distal end of the housing; an interior cavity disposed in the housing; a piston disposed in the interior cavity; a button coupled to the piston and disposed on the housing, wherein the button is configured to actuate the piston for pumping fluid through the housing; a fluid connector disposed at the proximal end of the housing; a fluid entry chamber disposed in the interior cavity on a proximal side of the piston; a fluid entry valve disposed on a proximal side of the fluid entry chamber, the fluid entry valve comprising a one-way valve that permits fluid flow to the fluid entry chamber from the fluid connector and prevents fluid flow out of the fluid entry chamber to the fluid connector; a fluid exit chamber disposed in the interior cavity on a distal side of the piston; a fluid exit valve disposed on a distal side of the fluid exit chamber; and a fluidic channel extending through the piston between a distal side of the fluid entry chamber and a proximal side of the fluid exit chamber, wherein the fluidic channel is segmented into a plurality of sub-channels, wherein each of the sub-channels terminates in a piston valve, wherein fluid exiting a first one of the sub-channels is configured to feed into a second one of the sub-channels. ### Claim 2 (depends on 1) The medical instrument of claim 1, further comprising: a pre-fill chamber; a sealing member configured to seal the pre-fill chamber; and an interface member having a proximal end configured to couple to a fluid source, a distal end configured to extend through the sealing member, and a fill port configured to deliver fluid from the fluid source to the pre-fill chamber, wherein rotation of the interface member relative to the sealing member is configured to urge movement of the sealing member to isolate the fill port from the pre-fill chamber. ### Claim 3 (depends on 1) The medical instrument of claim 1, further comprising: a pre-fill chamber; a sealing member configured to seal the pre-fill chamber, the sealing member being translatable along a longitudinal axis of the housing and rotatably fixed with respect to the housing, the sealing member having an opening extending therethrough, and a first spiral ramp; and an interface member having a proximal end, a distal end, a connector at the proximal end of the interface member configured to couple to a fluid source, a projection at the distal end of the interface member extending through the opening of the sealing member, a fill port on a lateral side of the projection, and a second spiral ramp configured to mate with the first spiral ramp of the sealing member, the interface member being rotatable about the longitudinal axis of the housing within a limited range of rotation, and translatably fixed along the longitudinal axis with respect to the housing, wherein rotation of the interface member within the limited range is configured to drive the sealing member distally along the longitudinal axis, via engagement between the first and second spiral ramps, to slide a seal past the fill port to isolate the fill port from the pre-fill chamber. ### Claim 4 (depends on 1) The surgical instrument of claim 1, further comprising a dose adjustment member coupled to the piston, wherein the dose adjustment member is adjustable to modify a length of travel of the piston and thereby change a volume of the fluid delivered upon the forward stroke of the piston. ### Claim 5 (depends on 1) The medical instrument of claim 1, wherein the elongate tubular housing has a lateral exterior surface that provides a grip for a human hand, and wherein the button is disposed on a lateral side of the elongate tubular housing. ### Claim 6 (depends on 1) The medical instrument of claim 1, wherein the button comprises a first sloped surface, wherein the piston comprises a second sloped surface, and wherein sliding engagement between the first sloped surface and the second sloped surface is configured to actuate a stroke of the piston. ### Claim 7 (depends on 1) The medical instrument of claim 1, wherein one of the button or the piston comprises a sloped surface, wherein the other of the button or the piston comprises a wheel, and wherein engagement between the sloped surface and the wheel is configured to actuate a stroke of the piston. ### Claim 8 (depends on 1) The medical instrument of claim 1, wherein a forward stroke of the piston causes compression of the fluid exit chamber and expansion of the fluid entry chamber. ### Claim 9 (depends on 8) The medical instrument of claim 8, wherein the compression of the fluid exit chamber is configured eject fluid from the fluid exit chamber to the tool section, and wherein the expansion of the fluid entry chamber is configured to draw fluid into the fluid entry chamber from a fluid source. ### Claim 10 (depends on 1) The medical instrument of claim 1, wherein the tool section comprises an ophthalmic blade at a distal end and a lumen; wherein the housing is configured to couple to a viscoelastic syringe; and wherein the piston is configured to transfer viscoelastic fluid from the viscoelastic syringe to the lumen. ### Claim 11 (depends on 10) The medical instrument of claim 10, wherein the ophthalmic blade comprises a dual-blade tip for incising a trabecular meshwork. ### Claim 12 (depends on 1) The medical instrument of claim 1, wherein the fluid connector is a luer lock connector configured to attach to a fluid source. ### Claim 13 (depends on 1) The medical instrument of claim 1, wherein a backward stroke of the piston is configured to transfer fluid from the fluid entry chamber to the fluid exit chamber. ### Claim 14 (depends on 1) The medical instrument of claim 1, wherein the piston is biased towards the proximal end, wherein release of the button is configured to cause a backward stroke of the piston towards the proximal end. ### Claim 15 (depends on 1) The medical instrument of claim 1, further comprising: a lock mechanism configured to lock the piston in a forward position, wherein the lock mechanism comprises a stop member on the piston and a twistable member configured to abut the stop member. ### Claim 16 (depends on 1) The medical instrument of claim 1, further comprising: a lock mechanism configured to lock the piston in a forward position, wherein the lock mechanism comprises a tab on the button that is slidable into the housing to hold the button in a depressed position.