# US 10,946,057 B2 · Antiseptics

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 10,946,057 B2
- Document ID: US10946057B2
- Status: Granted
- Kind: B2
- Application number: 15/824,763
- Filed: 2017-11-28
- Published: 2018-03-22
- Granted: 2021-03-16
- Earliest claimed: 2007-08-24
- Assignees: Insight Health Limited
- Applicants: Insight Health Limited
- Inventors: Tony Worthington; Tarja Karpanen
- Web page: https://patentgrep.com/patent/US10946057B2

## CPC

- A61K 36/53: Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K 31/045: Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K 31/05: Phenols {(cannabinoids A61K31/658)}
- A61K 31/155: Amidines ([IMAGE cpc-sch-A61K-1029.gif]), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A61K 36/61: Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
- A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61P 17/00: Drugs for dermatological disorders
- A61P 31/00: Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P 31/02: Local antiseptics
- A61P 31/04: Antibacterial agents
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention is based on the surprising antiseptic nature of chlorhexidine when combined with essential oils. It has been found that chlorhexidine, combined with an essential oil, is surprisingly effective at penetrating the skin surface and providing an antiseptic effect within the skin. It has also been found that a combination of chlorhexidine and eucalyptus oil is surprisingly effective as an antimicrobial against Staphylococcus epidermidis.

## Claims

### Claim 1

A disinfectant composition comprising:
0.5% to 2.5% chlorhexidine by weight (w/v);
60% to 80% isopropyl alcohol (v/v); and
eucalyptus oil in an amount of up to 10% (v/v).

### Claim 2 (depends on 1)

The disinfectant composition according to claim 1, wherein the chlorhexidine is chlorhexidine digluconate.

### Claim 3 (depends on 1)

The disinfectant composition according to claim 1, wherein the composition comprises eucalyptus oil in an amount of up to 5% (v/v).

### Claim 4 (depends on 1)

The disinfectant composition according to claim 1, wherein the composition comprises from 5% to 10% eucalyptus oil (v/v).

### Claim 5 (depends on 1)

The disinfectant composition according to claim 1, wherein the chlorhexidine, eucalyptus oil and isopropyl alcohol are the only antimicrobial agents in the composition.

### Claim 6 (depends on 1)

The disinfectant composition according to claim 1, wherein the composition is effective at sterilising an abiotic surface.

### Claim 7 (depends on 1)

The disinfectant composition according to claim 1, wherein the composition is effective at eliminating a biofilm on an abiotic surface.

### Claim 8 (depends on 1)

The disinfectant composition according to claim 1, wherein the composition is impregnated on a hard-surface wipe.

### Claim 9

A method of disinfecting a surface comprising:
contacting the surface with a disinfectant composition comprising:
0.5% to 2.5% chlorhexidine by weight (w/v);
60% to 80% isopropyl alcohol (v/v); and
eucalyptus oil in an amount of up to 10% (v/v).

### Claim 10 (depends on 9)

The method according to claim 9, wherein the chlorhexidine is chlorhexidine digluconate.

### Claim 11 (depends on 9)

The method according to claim 9, wherein the composition comprises eucalyptus oil in an amount of up to 5% (v/v).

### Claim 12 (depends on 9)

The method according to claim 9, wherein the composition comprises from 5% to 10% eucalyptus oil (v/v).

### Claim 13 (depends on 9)

The method according to claim 9, wherein the surface is an abiotic surface.

### Claim 14 (depends on 9)

The method according to claim 9, wherein the surface comprises a biofilm.

### Claim 15 (depends on 9)

The method according to claim 9, wherein the composition is impregnated on a hard-surface wipe.