Controlled release core-shell particles and suspensions including the same

A composition comprising:

• a dispersion medium comprising:
• an aqueous solution;
• a first active ingredient, wherein the first active ingredient is a source of vitamin C and a single dose of the composition to be administered comprises an amount of 100 to 2000 mg of vitamin C;
• and
• a first polymer, wherein the first polymer is a polysaccharide;
• and
• a dispersed phase comprising:
• a population of particles, each particle comprising:
• a core comprising:
• a second active ingredient, wherein the second active ingredient is a multivalent cation and a single dose of the composition to be administered comprises an amount of 5 to 40 mg of the multivalent cation;
• a second polymer, wherein the second polymer is selected from the group consisting of alginic acid, sodium alginate, potassium alginate, calcium alginate, agar, guar gum, and xanthan gum;
• and
• an aqueous solution;
• a shell, substantially surrounding the core, the shell comprising:
• a third polymer, wherein the third polymer is a water insoluble cellulose derivative;
• a plurality of lipophilic carriers;
• and
• a third active ingredient, wherein the third active ingredient is a source of cholecalciferol and a single dose of the composition to be administered comprises an amount of 5 to 30 mcg of cholecalciferol;
• and
• a plurality of emulsifying agents,
• wherein:
• at least 50% by weight of the second active ingredient is released within 2 hours after consumption;
• and
• at least 70% by weight of the third active ingredient is released within 2 hours after consumption.