# US 10,945,943 B2 · Extract of dragon fruit flower, method for preparing the same, use thereof, and skin complexion improved composition thereof

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- Number: US 10,945,943 B2
- Document ID: US10945943B2
- Status: Granted
- Kind: B2
- Application number: 16/022,119
- Filed: 2018-06-28
- Published: 2019-01-10
- Granted: 2021-03-16
- Earliest claimed: 2017-06-30
- Assignees: M.H. Biotechnology Corporation, Ltd.
- Applicants: M.H. Biotechnology Corporation, Ltd.
- Inventors: Hsiang-Hsun Chiang
- Web page: https://patentgrep.com/patent/US10945943B2

## CPC

- A61K 8/9789: Magnoliopsida [dicotyledons]
- A61K 36/33: Cactaceae (Cactus family), e.g. pricklypear or Cereus
- A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like
- A61Q 19/007: {Preparations for dry skin}
- A61Q 19/02: for chemically bleaching or whitening the skin
- A61Q 19/08: Anti-ageing preparations
- A61K 2236/00: Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

The present invention provides an extract of dragon fruit flower. The extract of dragon fruit flower is prepared by the following steps. A dragon fruit flower is provided. The dragon fruit flower is dried and then cut into pieces. An extraction process is provided, which includes a mixing step, a heating step, a cooling step, a reheating step, and an extracting step. In the mixing step, the pieces of the dragon fruit flower are mixed with an alcohol solution to obtain a mixture for processing the following steps. After finishing the extraction process, the mixture is separated into a solid part and a liquid part, wherein the liquid part includes the extract of the dragon fruit flower.

## Claims

### Claim 1

A method for preparing an extract of a dragon fruit flower, comprising:
providing the dragon fruit flower;
drying the dragon fruit flower, and then cutting the dragon fruit flower into chips after drying so as to obtain a plurality of dragon fruit flower pieces;
performing an extraction process, wherein the extraction process comprises:
providing a mixing step, wherein an alcohol solution is mixed with the dragon fruit flower pieces so as to form a mixture, and the alcohol solution is a glycerol solution;
providing a heating step, wherein the mixture is heated up to a heating temperature and then is reacted for a heating time;
providing a cooling step, wherein the mixture is cooled down to a room temperature and then is rested for a cooling time;
providing a reheating step, wherein the mixture is heated up to a reheating temperature and then is reacted for a reheating time; and
providing an extracting step, wherein the mixture is cooled down to the room temperature and then is stirred and reacted for an extracting time, and
removing a solid component from the mixture so as to obtain an extract liquid, wherein the extract liquid comprises the extract of the dragon fruit flower.

### Claim 2 (depends on 1)

The method of claim 1, wherein a volume percent concentration of the glycerol solution ranges from 10% to 50%.

### Claim 3 (depends on 2)

The method of claim 2, wherein the volume percent concentration of the glycerol solution ranges from 15% to 40%.

### Claim 4 (depends on 1)

The method of claim 1, wherein a weight ratio of the dragon fruit flower pieces to the alcohol solution in the mixing step ranges from 1:1 to 1:10.

### Claim 5 (depends on 4)

The method of claim 4, wherein the weight ratio of the dragon fruit flower pieces to the alcohol solution in the mixing step ranges from 1:2 to 1:6.

### Claim 6 (depends on 1)

The method of claim 1, wherein the heating temperature ranges from 40° C. to 70° C.

### Claim 7 (depends on 6)

The method of claim 6, wherein the heating temperature ranges from 50° C. to 60° C.

### Claim 8 (depends on 1)

The method of claim 1, wherein the heating time ranges from 6 hours to 10 hours.

### Claim 9 (depends on 8)

The method of claim 8, wherein the heating time is 8 hours.

### Claim 10 (depends on 1)

The method of claim 1, wherein the cooling time ranges from 20 hours to 28 hours.

### Claim 11 (depends on 10)

The method of claim 10, wherein the cooling time is 24 hours.

### Claim 12 (depends on 1)

The method of claim 1, wherein the reheating temperature ranges from 40° C. to 70° C.

### Claim 13 (depends on 12)

The method of claim 12, wherein the reheating temperature ranges from 50° C. to 60° C.

### Claim 14 (depends on 1)

The method of claim 1, wherein the reheating time ranges from 6 hours to 10 hours.

### Claim 15 (depends on 14)

The method of claim 14, wherein the reheating time is 8 hours.

### Claim 16 (depends on 1)

The method of claim 1, wherein the extracting time ranges from 5 days to 9 days.

### Claim 17 (depends on 16)

The method of claim 16, wherein the extracting time is 7 days.

### Claim 18 (depends on 1)

The method of claim 1, wherein the solid component is removed by a centrifugation method, a filtration method, or a combination thereof.