Recovery and processing of human embryos formed in vivo

A method, comprising:

• placing a device trans-vaginally into a cervical canal of a human;
• delivering fluid through the device to a uterus of the human and aspirating fluid and entrained one or more blastocysts from the uterus;
• performing a biopsy procedure on the one or more recovered blastocysts to remove one or more of a biopsied trophectoderm cells or an inner cell mass from the one or more recovered blastocysts;
• freezing the one or more of the biopsied trophectoderm cells or inner cell mass recovered from the one or more recovered blastocysts following the biopsy procedure;
• performing at least one molecular diagnostic assay test on the one or more biopsied trophectoderm cells or inner cell mass recovered from the one or more recovered blastocysts, wherein the at least one molecular diagnostic assay test is selected from the group consisting of genome hybridization, microarray gene chips, exome sequencing, and analysis of the entire human genome;
• and
• administering a sufficient dosage amount of a GnRH antagonist to cause corpus luteum apoptosis leading to desynchronization of the endometrium of the human prior to, during or following recovery of the one or more blastocysts from the uterus.

A method, comprising:

• placing a device trans-vaginally into a cervical canal of a human;
• delivering fluid through the device to a uterus of the human and aspirating fluid and entrained one or more blastocysts from the uterus;
• performing at least one molecular diagnostic assay test on the one or more recovered blastocysts, wherein the at least one molecular diagnostic assay test is selected from the group consisting of genome hybridization, microarray gene chips, exome sequencing, and analysis of the entire human genome;
• and
• administering a sufficient dosage amount of a GnRH antagonist to cause corpus luteum apoptosis leading to desynchronization of the endometrium of the human prior to, during or following recovery of the one or more blastocysts from the uterus.