# US 10,945,711 B2 · Tissue sampling device

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- Number: US 10,945,711 B2
- Document ID: US10945711B2
- Status: Granted
- Kind: B2
- Application number: 14/951,499
- Filed: 2015-11-25
- Published: 2016-03-17
- Granted: 2021-03-16
- Earliest claimed: 2013-05-27
- Assignees: FUJIFILM Corporation
- Applicants: FUJIFILM Corporation
- Inventors: Takumi Dejima; Masayuki Iwasaka; Shinichi Yamakawa; Manabu Miyamoto
- Web page: https://patentgrep.com/patent/US10945711B2

## CPC

- A61B 10/0266: {means for severing sample}
- A61B 8/0841: {for locating instruments}
- A61B 8/12: in body cavities or body tracts, e.g. by using catheters
- A61B 1/04: combined with photographic or television appliances
- A61B 2010/045: {Needles (pointed biopsy devices with vacuum aspiration A61B10/0283)}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A tissue sampling device includes a flexible sheath 34; a needle tube 35 which is inserted into the sheath 34 so as to advance and retreat and with which biological tissue is punctured; and an operating unit which is provided on a proximal side of the sheath 34 and is used for operating the advancing and retreating of the needle tube 35. This needle tube 35 has a distal portion provided with a slit 50 extending toward the proximal side from a distal opening 35c, and when the distal portion is in a state of protruding from a distal end of the sheath 34, at least a part of the distal portion is positioned further on the radially outside than the inner surface of the sheath when viewed from an axial direction of the needle tube 35.

## Claims

### Claim 1

A tissue sampling device comprising:
a flexible sheath;
a needle tube which is inserted into the sheath so as to advance and retreat where the needle tube is configured to puncture biological tissue; and
an operating unit which is provided on a proximal side of the sheath and is used to move the needle tube back and forth, comprising a casing and a slider slidably disposed in the casing, wherein the sheath is fixed to the casing, the slider is fixed to the needle tube, and the slider is adapted to slide relative to the casing so as to operate back and forth movement of the needle tube relative to the flexible sheath,
wherein the needle tube has a distal portion provided with a slit extending toward a proximal side of the needle tube from a distal opening, and when the distal portion is in a state of protruding from a distal end of the sheath, at least a part of the distal portion is positioned radially outside of an inner surface of the sheath when viewed from an axial direction of the needle tube,
wherein a distal side of the slit comprises a linear portion which is linearly formed along the axial direction of the needle tube toward the proximal side of the needle tube from the distal opening of the needle tube, and a proximal portion of the same slit is formed in a spiral shape with respect to the axial direction of the needle tube, wherein the linear portion of the slit is formed on only one side of the needle tube,
wherein the linear portion of the slit is parallel to the axial direction of the needle tube from the distal opening of the needle tube to the proximal portion of the slit, and the proximal portion of the slit extends from a proximal end of the linear portion of the slit toward the proximal side of the needle tube,
wherein the slit extends toward the proximal side of the needle tube from a portion other than a sharp tip portion of the distal opening of the needle tube, and the linear portion of the slit expands uniformly in order that the linear portion of the slit has a constant width upon protruding fully from the sheath.

### Claim 2 (depends on 1)

The tissue sampling device according to claim 1, wherein the distal portion of the needle tube is biased in a direction in which a curvature radius of at least one of edge portions of the needle tube facing each other across the slit is enlarged.

### Claim 3 (depends on 1)

The tissue sampling device according to claim 1, wherein the slit comprises a plurality of slits, the slits are provided in the distal portion of the needle tube.

### Claim 4 (depends on 1)

The tissue sampling device according to claim 1, wherein a diameter of the distal portion of the needle tube is made to be less than or equal to an inner diameter of the sheath when the distal portion thereof is accommodated in the sheath.