# US 10,945,597 B2 · Optical coherence tomography-based ophthalmic testing methods, devices and systems > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,945,597 B2 - Document ID: US10945597B2 - Status: Granted - Kind: B2 - Application number: 16/184,772 - Filed: 2018-11-08 - Published: 2019-03-28 - Granted: 2021-03-16 - Earliest claimed: 2008-03-27 - Assignees: Doheny Eye Institute - Applicants: Doheny Eye Institute - Inventors: Alexander C. Walsh; Paul G. Updike; Srinivas R. Sadda - Web page: https://patentgrep.com/patent/US10945597B2 ## CPC - A61B 3/102: {for optical coherence tomography [OCT]} - A61B 3/0025: {characterised by electronic signal processing, e.g. eye models} - A61B 3/0033: {characterised by user input arrangements} - A61B 3/0041: {characterised by display arrangements} - A61B 3/0091: {Fixation targets for viewing direction} - A61B 3/028: for testing visual acuity; for determination of refraction, e.g. phoropters - A61B 3/085: {for testing strabismus} - A61B 3/113: for determining or recording eye movement - A61B 3/117: for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes - A61B 3/132: {in binocular arrangement} - A61B 3/18: Arrangement of plural eye-testing or -examining apparatus - A61B 5/0066: {Optical coherence imaging} - A61B 5/0073: {by tomography, i.e. reconstruction of 3D images from 2D projections (A61B5/0066 takes precedence)} - G02C 7/027: {considering wearer's parameters} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G02C: SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES (trial frames for testing the eyes A61B3/04; goggles or eyeshields not having the same features as spectacles A61F9/00) ## Abstract In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's/subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and/or structural ophthalmic tests and output the test data. ## Claims ### Claim 1 An optical coherence tomography instrument comprising: an eyepiece for receiving an eye of a user; a target display visible through the eyepiece; a light source that outputs light that is directed through the eyepiece to the user's eye; an interferometer configured to produce optical interference using light reflected from the user's eye; an optical detector disposed so as to detect the optical interference; and electronics coupled to the target display and the detector and configured to provide an output based on optical coherence tomography measurements obtained using the interferometer, wherein the electronics are further configured to produce features on the target display of varying size and receive user responses to test the user's visual acuity. ### Claim 2 (depends on 1) The optical coherence tomography device of claim 1, further comprising an autofocus lens system configured to focus the features on the retina. ### Claim 3 (depends on 1) The optical coherence tomography device of claim 1, wherein an optical distance between the eyepiece and the features is adjustable. ### Claim 4 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to display the features simultaneously. ### Claim 5 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to display the features in series. ### Claim 6 (depends on 1) The optical coherence tomography device of claim 1, wherein the features are alphanumeric symbols. ### Claim 7 (depends on 6) The optical coherence tomography device of claim 6, wherein the alphanumeric symbols vary in contrast, spacing, font and color. ### Claim 8 (depends on 1) The optical coherence tomography device of claim 1, wherein the user responses are audible. ### Claim 9 (depends on 1) The optical coherence tomography device of claim 1, further comprising: a microphone input device configured to receive user responses; and the electronics are configured process the user responses and determine an accuracy of the user responses. ### Claim 10 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to test the user's visual acuity on both eyes simultaneously. ### Claim 11 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to test the user's visual acuity on both eyes sequentially. ### Claim 12 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to compare the user responses to a normative database. ### Claim 13 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to generate various statistics based on the user responses. ### Claim 14 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to output results of the visual acuity test. ### Claim 15 (depends on 1) The optical coherence tomography device of claim 1, wherein the visual acuity test comprises eye tracking methodologies. ### Claim 16 (depends on 1) The optical coherence tomography device of claim 1, further configured to test the user's visual acuity based on the user response to a last set of features that did not fail termination criteria. ### Claim 17 (depends on 1) The optical coherence tomography device of claim 1, wherein the features are optokinetic targets, and wherein the user responses are responsive eye movements. ### Claim 18 (depends on 17) The optical coherence tomography device of claim 17, wherein the electronics are configured to vary the frequency, speed, color, and contrast of the optokinetic targets. ### Claim 19 (depends on 1) The optical coherence tomography device of claim 1, wherein the electronics are configured to produce suppression stimuli on the target display.