Down-regulating gene expression in insect plants
AssigneeDevgen NV
InventorsThierry Bogaert, Romaan Raemaekers, Yann Naudet
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Abstract
The present invention relates to the prevention and/or control of infestation by insect pest species. In particular, the invention relates to down-regulation of expression of target genes in insect pests using interfering ribonucleic acid (RNA) molecules. Also described are transgenic plants that (i) express or are capable of expressing interfering RNAs of the invention and (ii) are resistant to infestation by insect pest species. Compositions containing the interfering RNAs of the invention are also provided.
Claims26
An interfering ribonucleic acid (RNA) molecule which comprises at least one double-stranded region, wherein said double-stranded region comprises a sense RNA strand annealed by complementary basepairing to an antisense RNA strand, wherein the interfering RNA molecule is encoded by a nucleic acid molecule comprising:
- (i) a nucleotide sequence that is at least 95% identical to any of SEQ ID NOs:
- 1, 21, or the complement thereof;
- or
- (ii) a nucleotide sequence comprising at least 21 contiguous nucleotides of any of SEQ ID NOs:
- 1, 21, or the complement thereof.
Dependencies are inferred from the claim text.