Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions

A method for determining at least one characteristic of at least one structure using a catheter, the catheter including an imaging system coupled to the catheter by a junction and controlled by a computer arrangement,

• the catheter comprising at least one optical fiber,
• the imaging system comprising at least one electro-magnetic radiation source coupled to the at least one optical fiber, and
• the computer arrangement comprising a processor,
• the method comprising:
• receiving, by the computer arrangement and from the imaging system via the junction, first data associated with the at least one structure;
• determining, by the computer arrangement, a distance between the catheter and the at least one structure based on the first data;
• receiving, by the computer arrangement and from the imaging system via the junction, second data associated with the at least one structure which is different from the first data,
• wherein the first and second data are obtained from substantially the same location on or in the at least one structure, and
• wherein the first data include structural information;
• correcting, by the computer arrangement, a signal intensity associated with the second data based on the distance between the catheter and the at least one structure to produce corrected second data;
• ascertaining, by the computer arrangement, further information associated with the at least one structure based on the corrected second data;
• and
• determining, by the computer arrangement, the at least one characteristic of the at least one structure based on the further information.