Testing device, microfluidic chip and nucleic acid testing method
AssigneesNanyang Technological University, Agency for Science, Technology and Research, The Methodist Hospital
InventorsJoseph Sylvester Chang, Geok Soon Lim, Lei Zhang, Zhiping Wang, Ruige Wu, Stephen T. C. Wong, Kemi Cui
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Abstract
A testing device is provided. The testing device includes a capturing tool and a microfluidic chip having a plurality of chambers connected in a network, a sample receiving port connected to the network, and a guide structure configured to receive the capturing tool, wherein the capturing tool is configured to capture sample in a distal position from the guide structure and further configured to transfer the captured sample to the sample receiving port in a proximal position from the guide structure.
Claims9
A testing device comprising:
- a biopsy needle comprising a cutting cannula and an inner stylet which is movable along the cutting cannula;
- and
- a microfluidic chip having
- a plurality of chambers connected in a network,
- a sample receiving port connected to the network, and
- a guide structure in the form of a wall structure protruding from a surface of the microfluidic chip at an edge of the sample receiving port,
- wherein a portion of the cutting cannula is received on the guide structure such that a longitudinal axis of the biopsy needle is substantially parallel to the surface of the microfluidic chip,
- wherein the inner stylet comprises a notch,
- wherein an opening at the portion of the cutting cannula is directed towards the sample receiving port, and
- wherein the inner stylet is movable relative to the cutting cannula to position the notch to capture a sample in a distal position from the guide structure and the inner stylet is further movable relative to the cutting cannula to position the notch to transfer, through the opening of the cutting cannula, the captured sample to the sample receiving port in a proximal position to the guide structure, whereby the guide structure directs the captured sample from the opening of the cutting cannula towards the sample receiving port.
The testing device as claimed in 6, further comprising:
- a main body encasing the frame structure and the microfluidic chip, wherein the main body is configured to receive the biopsy needle such that the biopsy needle is received by the guide structure of the microfluidic chip on the frame structure of the testing device;
- and
- a handgrip attached to the main body.
Dependencies are inferred from the claim text.