Intranasal vector vaccine against porcine epidemic diarrhea
OwnerVeljko Nikolin, Andreas Galleiinventors
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Abstract
The present invention relates to the field of (vector) vaccines, and especially to a canine distemper virus (CDV) vector comprising a heterologous nucleotide sequence which encodes a porcine epidemic diarrhea virus (PEDV) antigen. Said PEDV antigen is preferably a PEDV spike (S) protein. The viral vector of the present invention is useful for producing an immunogenic composition or vaccine for intranasally immunizing sows, and thereby protecting piglets, suckled by said sows, against the clinical signs associated with a PEDV infection.
Claims20
A canine distemper virus (CDV) vector comprising a heterologous nucleotide sequence of interest, wherein said heterologous nucleotide sequence of interest encodes a porcine epidemic diarrhea virus (PEDV) antigen wherein the PEDV antigen is a PEDV S protein.
Dependencies are inferred from the claim text.