Back to results
US 10,900,057 B2Granted
Recombinant microorganisms for the production of fatty amines
AssigneeGenomatica, Inc.
InventorsStephen B. Del Cardayre, Louis G. Hom
Life of this patent
Estimating the term…
Abstract
The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof. Further contemplated are cultured recombinant host cells as well as methods of producing fatty amines by employing these host cells.
Claims20
A recombinant bacterial cell for production of a fatty amine, wherein the fatty amine has a carbon chain length of between 5 to 24 carbons, comprising:
- (i) one or more expressed genes that encode an exogenous biosynthetic enzyme having thioesterase activity of EC number 3.1.2.-, 3.1.1.5, or 3.1.2.14;
- (ii) one or more expressed genes that encode an exogenous biosynthetic enzyme having carboxylic acid reductase activity of EC number 1.2.99.6;
- and
- (iii) one or more expressed genes that encode an exogenous biosynthetic enzyme having aminotransferase (EC number 2.6.1) or amine dehydrogenase activity (EC number 1.4.9, 1.4.98, 1.4.99), wherein said recombinant bacterial cell produces the fatty amine in vivo.
1 more element
Dependencies are inferred from the claim text.