Back to results
US 10,898,878 B2Granted
Adsorbent material
AssigneeShowa Denko Materials Co., Ltd.
InventorsMasashi Maruyama, Nanae Yamashita, Yuzuru Shimazaki, Hiroshi Yoshida, Keisuke Shibuya
Life of this patent
Estimating the term…
Abstract
An object of the present invention is to provide an adsorbent material having high dispersibility and reversibility. The adsorbent material has a polymer material having a plurality of functional groups ionizable in water and exhibiting no lower limit critical solution temperature, an adsorption site capable of interacting with a target substance, and a carrier.
Claims10
An adsorbent material, comprising:
- a polymer material having a plurality of functional groups ionizable in water and exhibiting no lower limit critical solution temperature;
- an adsorption site capable of interacting with a target substance;
- and
- a carrier,
- wherein the polymer material is a polylysine, a dendrimer having a plurality of amino groups, a dendrimer having a plurality of imino groups, a polyethyleneimine, a polyallylamine, a polyglutamic acid, or a polymer material having these as a partial structure;
- wherein the adsorption site is at least one selected from protein A partial structures or mimetic molecules, protein G partial structures or mimetic molecules, protein L partial structures or mimetic molecules, sugar chain-bonding molecules, thiophilic ligands, and antigens or antigen partial structures;
- and
- wherein the polymer material and the adsorption site are directly bound to each other, or the polymer material and the adsorption site are not bound to each other, but are immobilized at different positions on the carrier.
5 more elements
A method for purifying a target substance, comprising:
- contacting a solution comprising the target substance with an adsorbent material comprising,
- a polymer material having a plurality of functional groups ionizable in water and exhibiting no lower limit critical solution temperature;
- an adsorption site capable of interacting with the target substance;
- and
- a carrier,
- wherein the polymer material is a polylysine, a dendrimer having a plurality of amino groups, a dendrimer having a plurality of imino groups, a polyethyleneimine, a polyallylamine, a polyglutamic acid, or a polymer material having these as a partial structure;
- wherein the adsorption site is at least one selected from protein A partial structures or mimetic molecules, protein G partial structures or mimetic molecules, protein L partial structures or mimetic molecules, sugar chain-bonding molecules, thiophilic ligands, and antigens or antigen partial structures;
- and
- wherein the polymer material and the adsorption site are directly bound to each other, or the polymer material and the adsorption site are not bound to each other, but are immobilized at different positions on the carrier;
- and
- applying a change in an external environment wherein
- an ionization rate of the polymer material changes in response to the change in the external environment, and
- the change in the external environment is a change in temperature, salt concentration, permittivity or pH of a solution in contact with the adsorbent material.
10 more elements
Dependencies are inferred from the claim text.