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US 10,896,751 B2Granted
Storage and dispensing devices for administration of oral transmucosal dosage forms
AssigneeAcelRx Pharmaceuticals, Inc.
InventorsAndrew Poutiatine, Bruce Edwards, Charles Rampersaud, Pamela Palmer, Bradley Blackwood, Benjamin K. Yaffe
Life of this patent
Estimating the term…
Abstract
Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.
Claims21
An apparatus, comprising:
- a housing defining an actuation pathway and a channel in communication with the actuation pathway;
- a delivery member, at least a portion of the delivery member being disposed within the actuation pathway such that a distal end portion of the delivery member and a distal end portion of the housing define a volume configured to contain a drug-containing tablet, the delivery member configured to move relative to the housing in a distal direction to expel the drug-containing tablet from the volume, the delivery member including a protrusion configured to engage a portion of the housing to limit movement of the delivery member relative to the housing in a proximal direction, the delivery member including an elongate protrusion slidably disposed within the channel, an edge of the elongate protrusion configured to limit movement of the delivery member relative to the housing in the distal direction;
- and
- a removable safety member configured to engage the delivery member to prevent movement of the delivery member relative to the housing in the distal direction prior to removal of the safety member.
1 more element
An apparatus, comprising:
- a housing including a first portion coupled to a second portion to define an actuation pathway;
- a delivery member, at least a portion of the delivery member being disposed within the actuation pathway such that a distal end portion of the delivery member and a distal end portion of the housing define a volume configured to contain a drug-containing tablet, the delivery member configured to move relative to the housing in a distal direction to expel the drug-containing tablet from the volume,
- at least one of the first portion or second portion of the housing is configured to deform when the delivery member is moved in the distal direction relative to the housing to produce an opening through which the drug-containing tablet can be expelled;
- and
- a safety member removably coupled to the apparatus such that the safety member contacts a portion of the delivery member to prevent movement of the delivery member relative to the housing in the distal direction to expel the drug-containing tablet from the volume.
2 more elements
An apparatus, comprising:
- a housing defining an actuation pathway, a proximal end portion of the housing defining a channel and including a bridge member disposed in the channel;
- and
- a delivery member, at least a portion of the delivery member being disposed within the actuation pathway such that a distal end portion of the delivery member and a distal end portion of the housing define a volume configured to contain a drug-containing tablet, the delivery member configured to move relative to the housing in a distal direction to expel the drug-containing tablet from the volume through an opening defined by the distal end portion of the housing, the delivery member including a first protrusion configured to engage a portion of the housing to limit movement of the delivery member relative to the housing in a proximal direction, the delivery member including a second protrusion slidably disposed within the channel and configured to engage the bridge member,
- the bridge member configured to limit movement of the delivery member in the distal direction, the bridge member configured to deform when a force applied by the delivery member in the distal direction exceeds a predetermined threshold to permit movement of the delivery member in the distal direction.
1 more element
Dependencies are inferred from the claim text.