Techniques of deformation analysis for quantification of vascular enlargement

An apparatus comprising one or more processors and a computer-readable memory storing non-transient instructions that when executed by the one or more processors cause the apparatus to:

• obtain a first volumetric imaging data for at least a segment of a vessel and determine a first 3-dimentional (3D) segmentation and model of the at least a segment of the vessel;
• obtain a second volumetric imaging data for the segment of the vessel;
• register the second volumetric imaging data to the first volumetric imaging data and determine a degree of deformation of an anatomic dimension of a vessel resulting from the registration;
• calculate a quantitative deformation metric using an optimized non-rigid transformation between the second volumetric imaging data and the first volumetric imaging data;
• and
• map the quantitative deformation metric to a 3D vessel surface model for display.

A system comprising:

• an imaging device for generating volumetric imaging data,
• one or more processors, and
• a computer-readable memory storing non-transient instructions that when executed by the one or more processors cause the one or more processors to,
• obtain a first volumetric imaging data for at least a segment of a vessel and determine a first 3-dimentional (3D) segmentation and model of the at least a segment of the vessel;
• obtain a second volumetric imaging data for the segment of the vessel;
• register the second volumetric imaging data to the first volumetric imaging data and determine a degree of deformation of an anatomic dimension of a vessel resulting from the registration;
• calculate a quantitative deformation metric using an optimized non-rigid transformation between the second volumetric imaging data and the first volumetric imaging data;
• and
• map the quantitative deformation metric to a 3D vessel surface model for display.