Method for operating a laboratory system

A computer implemented method for operating a laboratory system, wherein the laboratory system comprises a plurality of laboratory instruments for processing biological samples and a control unit communicatively connected by a communication network, the method comprising:

• receiving and identifying a biological sample by one of the plurality of laboratory instruments;
• retrieving an order list from a database by the control unit, the list comprising a plurality of targets corresponding to the biological sample, each of the targets defining at least one processing steps to be carried out on the biological sample by at least one of the plurality of the laboratory instruments;
• selecting a workflow strategy by the control unit, wherein the workflow strategy defines at least one priority rules in processing the biological sample;
• retrieving workflow acceptance criterion by the control unit from a database corresponding to the workflow strategy;
• determining a sample workflow by the control unit for processing the biological sample based on the workflow strategy and the order list;
• determining by the control unit whether the sample workflow satisfies the workflow acceptance criterion;
• and
• in response to determining that the sample workflow does not satisfy the workflow acceptance criterion, refining workflow strategy by the control unit, refining workflow acceptance criterion by the control unit, and determining the sample workflow by the control unit based on the workflow strategy and the order list until the sample workflow satisfies the workflow acceptance criterion.