Microfluidic multi-well-based cell culture testing device
AssigneeQuantamatrix Inc.
InventorsYong Gyun Jung, Eun Geun Kim, Sung hoon Kwon, Jung Il Choi
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Abstract
A microfluidic multi-well-based cell culture testing device is provided. The multi-well-based cell culture testing device has an array structure of a plurality of aligned microfluidic well units. Each of the microfluidic well units comprises an inlet through which a first fluid enters, an accommodation compartment adapted to accommodate a second fluid therein, a microfluidic channel through which the first fluid flows, and an air outlet adapted to facilitate the entering of the first fluid.
Claims12
A microfluidic multi-well-based cell culture testing device that has an array structure of a plurality of aligned microfluidic well units, each of the microfluidic well units comprising
- an inlet comprises a recess, wherein the recess is exposed to air in an upward direction such that a first fluid is injected into the inlet from a top of the recess,
- an accommodation compartment adapted to accommodate a second fluid therein,
- a microfluidic channel through which the first fluid flows, and
- an air outlet adapted to facilitate the entering of the first fluid, wherein the air outlet
- comprises a second recess and is in direct contact with one end of the microfluidic
- channel, the inlet is in direct contact with another end of the microfluidic channel, and the
- air outlet is not in direct contact with the inlet,
- wherein the accommodation compartment is designed in the form of a well such that the entering second fluid is retained, and a capillary valve is formed where a portion of the lower lateral side of the accommodation compartment is in communication with a portion of the lateral side of the microfluidic channel such that the first fluid and the second fluid meet each other to form an interface, and
- the inlet and the accommodation compartment are spatially separated from each other and does not directly contact each other.
Dependencies are inferred from the claim text.