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US 10,894,132 B2Granted
Auto-injector
AssigneeSanofi-Aventis Deutschland GmbH
InventorsSimon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
Life of this patent
Estimating the term…
Abstract
An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
Claims25
An auto-injector for administering a dose of a liquid medicament, the auto-injector comprising:
- a tubular chassis telescopable in a tubular case;
- a carrier subassembly comprising a tubular carrier slidably arranged relative to the tubular chassis inside the tubular case, the tubular carrier adapted to contain a syringe with a hollow injection needle;
- a plunger configured to receive a load and to forward the load to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the tubular carrier;
- a control spring arranged around the tubular carrier for translating the tubular carrier in a proximal direction for insertion of the needle through the tubular chassis into an injection site, wherein the control spring is arranged to bias the tubular case against the tubular chassis in a distal direction so as to extend the tubular chassis out of a proximal end of the tubular case, wherein an insertion depth of the needle is defined by the tubular carrier abutting the tubular chassis in a predefined position, and wherein the tubular case is arranged to release or allow release of the control spring for needle insertion on translation of the tubular case in the proximal direction relative to the tubular chassis against a bias applied by the control spring into an advanced position;
- a plunger release mechanism coupled to the plunger, the plunger release mechanism configured to prevent axial translation of the plunger relative to the tubular carrier, wherein the plunger release mechanism comprises a releasable form-locking connection between the plunger and at least one of the tubular carrier and the tubular case, and wherein, when the tubular carrier reaches the predefined position during needle insertion, the plunger is configured to disengage from at least one of the tubular carrier and the tubular case under the load to received by the plunger;
- and
- a visual use indicator comprising at least one indicator window in the tubular case, wherein a part of the tubular chassis is arranged to be located behind the at least one indicator window when the tubular case is in a distal position biased by the control spring, wherein a tab on a first collar is located outwardly from the part of the tubular chassis after the first collar has been translated in the proximal direction during needle insertion, and wherein the tab and the part of the tubular chassis exhibit a visually distinctive feature.
4 more elements
An auto-injector for administering a dose of a liquid medicament, the auto-injector comprising:
- a tubular chassis telescopable in a tubular case;
- a carrier subassembly comprising a tubular carrier slidably arranged relative to the tubular chassis inside the tubular case, the tubular carrier adapted to contain a syringe with a hollow injection needle;
- a plunger configured to receive a load and to forward the load to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the tubular carrier;
- a control spring arranged around the tubular carrier for translating the tubular carrier in a proximal direction for insertion of the needle through the tubular chassis into an injection site, wherein the control spring is arranged to bias the tubular case against the tubular chassis in a distal direction so as to extend the tubular chassis out of a proximal end of the tubular case, wherein an insertion depth of the needle is defined by the tubular carrier abutting the tubular chassis in a predefined position, and wherein the tubular case is arranged to release or allow release of the control spring for needle insertion on translation of the tubular case in the proximal direction relative to the tubular chassis against a bias applied by the control spring into an advanced position;
- and
- a plunger release mechanism coupled to the plunger, the plunger release mechanism configured to prevent axial translation of the plunger relative to the tubular carrier, wherein the plunger release mechanism comprises at least one resilient arm on the tubular carrier arranged to be in a ramped engagement to the plunger so as to disengage the at least one resilient arm from the plunger under the load received by the plunger, wherein the plunger release mechanism comprises a releasable form-locking connection between the plunger and at least one of the tubular carrier and the tubular case, and wherein, when the tubular carrier reaches the predefined position during needle insertion, the plunger is configured to disengage from at least one of the tubular carrier and the tubular case under the load received by the plunger.
3 more elements
An auto-injector for administering a dose of a liquid medicament, the auto-injector comprising:
- a tubular chassis telescopable in a tubular case;
- a carrier subassembly comprising a tubular carrier slidably arranged relative to the tubular chassis inside the tubular case, the tubular carrier adapted to contain a syringe with a hollow injection needle;
- a plunger configured to receive a load and to forward the load to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the tubular carrier;
- a control spring arranged around the tubular carrier for translating the tubular carrier in a proximal direction for insertion of the needle through the tubular chassis into an injection site, wherein the control spring is arranged to bias the tubular case against the tubular chassis in a distal direction so as to extend the tubular chassis out of a proximal end of the tubular case, wherein an insertion depth of the needle is defined by the tubular carrier abutting the tubular chassis in a predefined position, wherein the tubular case is arranged to release or allow release of the control spring for needle insertion on translation of the tubular case in the proximal direction relative to the tubular chassis against a bias applied by the control spring into an advanced position, and wherein a proximal end of the control spring is coupled to the tubular chassis prior to needle insertion;
- and
- a plunger release mechanism coupled to the plunger, the plunger release mechanism configured to prevent axial translation of the plunger relative to the tubular carrier, wherein the plunger release mechanism comprises a releasable form-locking connection between the plunger and at least one of the tubular carrier and the tubular case, and wherein, when the tubular carrier reaches the predefined position during needle insertion, the plunger is configured to disengage from at least one of the tubular carrier and the tubular case under the load received by the plunger.
3 more elements
Dependencies are inferred from the claim text.