Fraction of melissa leaf extract having angiogenesis and MMP inhibitory activities, and composition comprising the same
AssigneeAngiolab, Inc.
InventorsMin-Young Kim, Jong Cheon Hahm, Byung Young Park, Eun Kyu Park, Hee Suk Lee
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Abstract
The present application describes an ethyl acetate fraction of Melissa leaf having excellent angiogenesis and MMP inhibitory activities, and a composition comprising the same.
Claims2
A method of reducing obesity in a subject, comprising administering to a subject in need thereof Melissa leaf extract, which has been extracted with 75% ethanol, and concentrated, and then the concentrated alcohol extract is suspended in water, and fractionated with ethyl acetate, and dried to obtain the ethyl acetate fraction of Melissa leaf.
A method of reducing obesity in a subject, comprising (i) extracting Melissa leaf with 75% ethanol;
- (ii) concentrating the alcohol extract;
- (iii) suspending the concentrated alcohol extract in water;
- (iv) fractionating the alcohol extract in water with ethyl acetate;
- (v) drying the ethyl acetate fraction to obtain the ethyl acetate fraction of Melissa leaf;
- and administering to a subject in need thereof the obtained ethyl acetate fraction of Melissa leaf.
Dependencies are inferred from the claim text.