Methods for solid tumor treatment
AssigneeCrititech, Inc.
InventorsMike Baltezor, Gere diZerega, Charles Decedue, Sam Campbell, Matt McClorey
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Abstract
Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.
Claims22
A method for inhibiting metastasis in a subject with a malignant solid tumor, the method comprising administering to the subject an amount effective of a composition comprising taxane particles to inhibit metastasis, wherein the taxane is selected from the group consisting of paclitaxel and docetaxel, wherein the taxane particles comprise at least 95% by weight taxane or a pharmaceutically acceptable salt thereof, and wherein the taxane particles have a specific surface area (SSA) of at least 18 m2/g, and wherein the taxane particles include both agglomerated taxane particles and non-agglomerated taxane particles.
Dependencies are inferred from the claim text.