Methods and pharmaceutical compositions for the treatment of cancer
AssigneesInserm (Institut National de la Santa et de la Recherche Medicale), Universite Paris Diderot—Paris 7
InventorsAlain Couvineau, Valérie Gratio, Pascal Nicole, Thierry Voisin
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Abstract
The present invention relates to methods and pharmaceutical compositions for the treatment of cancer. More particularly, the present invention relates to a method of treating cancer in subject in need thereof comprising administering the subject with a therapeutically effective amount of at least one OX1R antagonist.
Claims11
A method of treating a colorectal cancer in a subject in need thereof, wherein cells of said cancer express orexin-1-receptor (OX1R), comprising administering to the subject a therapeutically effective amount of at least one OX1R antagonist to treat said colorectal cancer, wherein the OX1R antagonist is selected from the group consisting of SB408124, Suvorexant and Almorexant, and wherein said cells of said colorectal cancer expressing said OX1R.
Dependencies are inferred from the claim text.