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US 10,894,035 B2Granted
Use of indole compounds to stimulate the immune system
AssigneeDiaccurate
InventorsJacques Theze, Blanche Tamarit
Life of this patent
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Abstract
Methods for treating immunodeficiencies are provided using indole-based compounds.
Claims10
A method for treating a HIV-infected subject comprising administering to the subject a compound of formula A in an amount effective for restoring or stimulating CD4 T cell function in said subject,
- wherein:
- each X is independently an oxygen or sulfur atom;
- R1 is —(CH2)n—Ar wherein n is 0, 1 or 2 and Ar is a C5-C7 aromatic group;
- R2 is a C1-C4 alkyl;
- and
- R3 is —(O)m—(CH2)p—COOR4 wherein m is 0 or 1;
- p is 0, 1, or 2;
- and R4 is a hydrogen atom or a C1-C3 alkyl;
- or a salt, ester, hydrate, racemate, or enantiomer thereof.
6 more elements
Dependencies are inferred from the claim text.