Back to results
US 10,894,034 B2Granted
Anti-neoplastic compounds and methods targeting QSOX1
AssigneesArizona Board of Regents on behalf of Arizona State University, Mayo Foundation for Medical Education and Research
InventorsDouglas Lake, Erik Castle, Paul Hanavan, Douglas Faigel, Thai Ho
Life of this patent
Estimating the term…
Abstract
Compounds and methods involving inhibition of the enzymatic activity of QSOX1 (FIG. 13). The compounds and methods can be used in treatment of neoplastic cells, for example, to suppress tumor growth and invasion in a variety of cancers, including but not limited to myeloma and cancers of the breast, kidney, and pancreas.
Claims6
A pharmaceutical composition, comprising:
- or a pharmaceutically acceptable salt thereof;
- and
- (b) a pharmaceutically acceptable carrier.
A method for cancer treatment, comprising administering to a subject having a tumor an effective amount of compound SBI-183:
- or a pharmaceutically acceptable salt thereof, wherein said cancer is selected from a cancer of the breast, a cancer of the pancreas, a cancer of the kidney, and myeloma.
Dependencies are inferred from the claim text.