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US 10,894,017 B1Granted
Rapidly disintegrating solid oral dosage forms containing dasatinib
AssigneeXspray Pharma AB
InventorsPer Andersson, Thomas Meijer, Victor Söderberg
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Abstract
The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.
Claims20
A tablet for oral administration, comprising
- dasatinib (S)-1,2-propanediol solvate;
- at least one pharmaceutically acceptable excipient;
- and
- a coating layer;
- wherein the tablet releases at least 80% of the dasatinib within 20 minutes when the tablet is tested in a USP Type 2 apparatus in 500 mL of 0.01 M hydrochloric acid at about 37° C. and about 75 RPM;
- wherein the amount of dasatinib is equivalent to 100 mg dasatinib.
3 more elements
Dependencies are inferred from the claim text.