Nanoparticles for the encapsulation of compounds, preparation thereof and use of same
AssigneesCentro Nacional De TecnologíA Y Seguridad Alimentaria, Laboratorio Del Ebro, Universidad De Navarra
InventorsMaite Agüeros Bazo, Irene Esparza Catalán, Carolina González Ferrero, Carlos Javier González Navarro, Juan Manuel Irache Garreta, Ana Romo Hualde
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Abstract
The present invention relates to nanoparticles for encapsulating compounds, the preparation and uses thereof, comprising a casein matrix, a basic amino acid and a metal selected from a divalent metal, a trivalent metal and combinations thereof. Said nanoparticles can encapsulate a water soluble or fat soluble biologically active compound. The invention is applicable in the food, pharmaceutical and cosmetic sectors and in the nanotechnology sector.
Claims14
A composition comprising at least one nanoparticle and a carrier acceptable for oral administration of food or pharmaceuticals, wherein the nanoparticle comprises a casein matrix, lysine, a biologically active compound, and a metal selected from a divalent metal, a trivalent metal and combinations thereof, wherein the lysine molecules are adhered to the surface of the casein matrix, wherein the biologically active compound is encapsulated in the nanoparticle, and wherein the polydispersion value (PDI) is less than 0.3 over time.
A composition comprising at least one nanoparticle, and a carrier acceptable in food, pharmacy or cosmetics, wherein said nanoparticle comprises a casein matrix, a basic amino acid and a metal selected from a divalent metal, a trivalent metal and combinations thereof, the composition being selected from the group consisting of:
- a composition comprising:
- casein, between 10% and 50% by weight;
- folic acid, between 0.9% and 2.5% by weight;
- calcium, between 1% and 6% by weight;
- a basic amino acid, between 1% and 7% by weight;
- and
- a saccharide, between 30% and 80% by weight,
- wherein all the proportions are by weight with respect to the total weight of the composition, and
- a composition comprising:
- casein, between 10% and 50% by weight;
- folic acid, between 0.9% and 2.5% by weight;
- calcium, between 1% and 6% by weight;
- and
- a basic amino acid, between 1% and 7% by weight;
- a saccharide, between 20% and 55% by weight;
- and
- ascorbic acid, between 1% and 25%,
- wherein all the proportions are by weight with respect to the total weight of the composition.
Dependencies are inferred from the claim text.