Curable calcium phosphate compositions for use with porous structures and methods of using the same

An apparatus comprising:

• a porous metal structure comprising
• a porous substrate comprising a plurality of ligaments that define pores of the porous substrate, and
• a biocompatible metal coating on the plurality of ligaments of the porous substrate;
• and
• a curable calcium phosphate composition at least partially in contact with the porous metal structure and injection-perfused through an injection surface area of the porous metal structure into the pore space of the porous metal structure in an amount of at least 0.5 mL of the curable calcium phosphate composition per about 150 mm2 of the injection surface area, wherein a maximum injection force to inject by syringe more of the curable calcium phosphate composition through the injection surface area into the pore space of the porous metal structure such that the curable calcium phosphate composition reaches a depth of greater than 6 mm from a surface of the porous metal structure and greater than 10 pore diameters from the surface of the porous metal structure is less than 10 kgf, the curable calcium phosphate composition comprising
• calcium phosphate,
• a perfusion modifier, wherein the perfusion modifier is 0.5 wt % to 5 wt % of the curable calcium phosphate composition, wherein the perfusion modifier is methylcellulose, carboxymethylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose, a salt thereof or a combination thereof, and
• a physiologically acceptable fluid.