Diagnosis and anti-Mullerian hormone (AMH) administration for treatment of infertility for good-, intermediate- and poor-prognosis patients for in vitro fertilization in view of logistic regression models

A method of increasing a live birth rate in a subject, comprising:

• accessing an analysis tool that identifies an applicable one of different prognosis categories each containing a corresponding success percentage for an ascertained anti-Mü llerian hormone (AMH) level of a subject based upon the age of the subject, wherein the analysis tool:
• sets forth a success percentage that is correlated with an AMH level based upon an applicable age group,
• assigns the success percentage as applicable to a live birth rate, a live birth probability, a pregnancy rate with in vitro fertilization and a pregnancy probability with in vitro fertilization, and
• categorizes the assigned success percentage into an associated grouping for an applicable one of different prognosis categories;
• making a diagnosis by retrieving the associated grouping from the accessed analysis tool so as to provide a prognosis for increasing the live birth rate in the subject;
• and
• administering to the subject a composition having an effective amount of AMH protein in accord with the prognosis to achieve and maintain the AMH level over time of between:
• 5.0-6.5 ng/ml inclusive for the subject who is between 39-42 years old, 4.5-6.5 ng/ml inclusive for the subject who is between 36-38 years old, and 3.5-7.0 ng/ml for the subject who is under 36 years old,
• wherein the composition comprises SEQ ID NO:
• 1.

A method of terminating pregnancy or increasing miscarriage rate in a subject, comprising:

• accessing an analysis tool that identifies an applicable one of different prognosis categories each containing a corresponding success percentage for an ascertained anti-Mü llerian hormone (AMH) level of a subject based upon the age of the subject, wherein the analysis tool:
• sets forth a success percentage that is correlated with an AMH level based upon an applicable age group,
• assigns the success percentage as applicable to a live birth rate, a live birth probability, a pregnancy rate with in vitro fertilization and a pregnancy probability with in vitro fertilization, and
• categorizes the assigned success percentage into an associated grouping of the assigned success percentage for an applicable one of different prognosis categories;
• making a diagnosis by retrieving the associated grouping from the accessed analysis tool so as to provide a prognosis for terminating pregnancy or increasing miscarriage rate in the subject;
• and
• administering to the subject a composition having an effective amount of AMH protein in accord with the prognosis to achieve and maintain an AMH level that is higher than that of:
• 7.0 ng/ml for the subject being under 36 years old;
• and 6.5 ng/ml for the subject being 36-42 years old inclusive,
• wherein the composition comprises SEQ ID NO:
• 1.

A method of decreasing a pregnancy rate in a subject, comprising:

• accessing an analysis tool that identifies an applicable one of different prognosis categories each containing a corresponding success percentage for an ascertained anti-Mü llerian hormone (AMH) level of a subject based upon the age of the subject, wherein the analysis tool:
• sets forth a success percentage that is correlated with an AMH level based upon an applicable age group,
• assigns the success percentage as applicable to a live birth rate, a live birth probability, a pregnancy rate with in vitro fertilization and a pregnancy probability with in vitro fertilization, and
• categorizes the assigned success percentage into an associated grouping for an applicable one of different prognosis categories;
• making a diagnosis by retrieving the associated grouping from the accessed analysis tool so as to provide a prognosis for decreasing the pregnancy rate in the subject;
• and
• administering to the subject a composition having an effective amount of AMH protein in accord with the prognosis to achieve and maintain an AMH level that is higher than that of:
• 8.5 ng/ml for the subject being under 36 years old;
• 7.5 ng/ml for the subject being 36-38 years old inclusive;
• 7.0 ng/ml for the subject being 39-42 years old inclusive;
• and 7.5 ng/ml for the subject being over 42 years old,
• wherein the composition comprises SEQ ID NO:
• 1.