Sample analyzer and sample analysis method thereof
AssigneeShenzhen Mindray Bio-Medical Electronics Co., Ltd.
InventorsXiansuan Du, Yong Dai
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Abstract
A sample analyzer with an optical detection device and a sample analysis method of the sample analyzer are disclosed. The optical detection device includes a fluid chamber, a light source and a light detector. The fluid chamber includes an illumination zone. An analyte flows through the illumination zone so as to form a sample stream. The light source illuminates the illumination zone to excite cell articles, reacted with a reagent, of the sample stream to emit a light signal. The light detector detects the fluorescent lights and transforms it into an electric signal. The light detector can include a silicon photomultiplier.
Claims18
A sample analysis method for a sample analyzer, comprising:
- providing an analyte comprising cell particles treated with a reagent;
- providing an optical measurement device comprising a fluid chamber, a light source and a light detector comprising at least one silicon photomultiplier, wherein a light sensing area of the at least one silicon photomultiplier is smaller than a threshold value, a distortion of a pulse amplitude of an electrical signal is triggered when the light sensing area of the at least one silicon photomultiplier exceeds the threshold value, the electrical signal is generated according to an amount of dark pulse count overlapping on a single cell particle;
- when the analyte flows through the fluid chamber and forms a sample stream, illuminating the sample stream flowing through the fluid chamber by the light source to generate a light signal, and transforming the light signal into light signal information after the light detector receives the light signal;
- and
- classifying the cell particles according to the light signal information.
Dependencies are inferred from the claim text.