Back to results
US 10,883,077 B2Granted
Methods for controlling the growth of prokaryotic and eukaryotic cells
AssigneeInscripta, Inc.
InventorsPhillip Belgrader, Don Masquelier
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to methods for control of cell growth rates where cell growth is measured in situ. The methods are applicable to bacterial cells, mammalian cells, non-mammalian eukaryotic cells, plant cells, yeast cells, fungi, and archea.
Claims19
A cell growth device comprising:
- a housing;
- a motor;
- a thermal control device;
- a spectrophometer;
- a rotating growth vial comprising a vial comprising two or more paddles extending into an interior of the rotating growth vial from an interior surface of an outer wall of the rotating growth vial;
- a drive engagement mechanism configured to engage with the motor to spin the rotating growth vial;
- and a first light path through the vial for a light beam generated by the spectrophotometer;
- a processor programmed to accept input from a user and to direct the thermal control device to adjust a temperature of the rotating growth vial to grow the cells;
- an electrical connection configured to be electrically coupled to the thermal control device;
- and
- wherein the spectrophotometer measures an optical density of the cells in the rotating growth vial and through the electrical connection directs the processor to direct the thermal control device to adjust the temperature of the rotating growth vial to grow the cells to a target value at a target time.
8 more elements
A cell growth device comprising:
- a housing;
- a motor;
- a thermal control device;
- a spectrophometer;
- a rotating growth vial comprising a rotating growth vial comprising two or more paddles that extend from a center of the rotating growth vial toward an inner surface of an outer wall of the rotating growth vial;
- a drive engagement mechanism configured to engage with the motor to spin the rotating growth vial;
- and a first light path through the rotating growth vial for a light beam generated by the spectrophotometer;
- a processor programmed to accept input from a user and to direct the thermal control device to adjust a temperature of the rotating growth vial to grow the cells;
- an electrical connection configured to be electrically coupled to the thermal control device;
- and
- wherein the spectrophotometer measures an optical density of the cells in the rotating growth vial and through the electrical connection directs the processor to direct the thermal control device to adjust the temperature of the rotating growth vial to cool the rotating growth vial grow the cells to a target value at a target time.
8 more elements
Dependencies are inferred from the claim text.