2-benzopyrazinyl-n-heteroaryl-2-phenyl-acetamide compounds

A compound of formula I,

• wherein
• R1 is each independently selected from the group consisting of
• i) amino,
• ii) C1-6-alkyl,
• iii) C1-6-alkoxy,
• iv) cyano,
• v) halogen,
• vi) halogen-C1-6-alkyl,
• vii) halogen-C1-6-alkoxy, and
• viii) hydroxy;
• R2 is each independently selected from the group consisting of
• i) amino,
• ii) aryl substituted with (R3)k,
• iii) C1-6-alkyl,
• iv) C1-6-alkoxy,
• v) C2-6-alkynyl substituted with (R5)p,
• vi) cyano,
• vii) halogen,
• viii) halogen-C1-6-alkyl,
• ix) halogen-C1-6-alkoxy,
• x) heteroaryl substituted with (R4)l,
• xi) heterocyclyl substituted with (R7)r and
• xii) hydroxy;
• R3 is each independently selected from the group consisting of
• i) amino,
• ii) C1-6-alkyl,
• iii) C1-6-alkoxy,
• iv) cyano,
• v) halogen,
• vi) halogen-C1-6-alkyl,
• vii) halogen-C1-6-alkoxy, and
• viii) hydroxy;
• R4 is each independently selected from the group consisting of
• i) amino,
• ii) C1-6-alkyl,
• iii) C1-6-alkoxy,
• iv) cyano,
• v) halogen,
• vi) halogen-C1-6-alkyl,
• vii) halogen-C1-6-alkoxy,
• viii) heterocyclyl substituted with (R8)s, and
• ix) hydroxy;
• R5 is independently selected from the group consisting of
• i) heteroaryl substituted with (R6)q, and
• ii) C1-6-alkyl;
• R6 is independently selected from the group consisting of
• i) amino, and
• ii) C1-6-alkyl;
• R7 is independently selected from the group consisting of
• i) amino, and
• ii) C1-6-alkyl;
• R8 is independently selected from the group consisting of
• i) amino, and
• ii) C1-6-alkyl;
• Het is heteroaryl;
• k is 0, 1, 2 or 3;
• l is 0, 1 or 2;
• n is 0, 1, 2 or 3;
• m is 0, 1 or 2;
• p is 0, 1 or 2;
• q is 0, 1 or 2;
• r is 0, 1 or 2;
• s is 0, 1 or 2;
• or a pharmaceutically acceptable salt thereof.