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US 10,882,041 B2Granted
Systems and methods for mobile device analysis of nucleic acids and proteins
AssigneeNanobiosym, Inc.
InventorAnita Goel
Life of this patent
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Abstract
A portable system for extracting, optionally amplifying, and detecting nucleic acids or proteins using a compact integrated chip in combination with a mobile device system for analyzing detected signals, and comparing and distributing the results via a wireless network. Related systems and methods are provided.
Claims50
A system for analysis of a sample, comprising:
- a fluidic chip configured to perform a cycle of operations comprising:
- a) extracting a biological material from the sample in an extraction control module;
- b) generating one or more products from the biological material in an amplification control module;
- and
- c) detecting the one or more products in a detection control module;
- and
- a device configured to interface with the fluidic chip and comprising a processor configured to activate one or more of the control modules during a cycle of operations a)-c),
- wherein the control modules are configured to exert nanoscale control during the cycle of operations a)-c);
- and
- wherein the nanoscale control comprises at least one of:
- applying a stress to a molecular species;
- adjusting a rotational orientation of a molecular species;
- adjusting a translational position of a molecular species;
- and applying a tension to a molecular species.
11 more elements
A system for analysis of a sample, comprising:
- a fluidic chip configured to perform a cycle of operations comprising:
- a) extracting a biological material from the sample in an extraction control module;
- b) generating one or more products from the biological material in an amplification module;
- and
- c) detecting the one or more products in a detection control module;
- and
- a device configured to interface with the fluidic chip and comprising a processor configured to activate one or more of the control modules during a cycle of operations a)-c),
- wherein the extraction control module is configured to exert nanoscale control during the extraction of the biological material to control at least one at least one of a stress applied to molecules of the biological material, a rotational orientation of molecules of the biological material, a translational position of molecules of the biological material, and a tension applied to molecules of the biological material.
5 more elements
Dependencies are inferred from the claim text.