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US 10,881,775 B2Granted
Dialysis machine and ultrafiltration
AssigneeQuanta Dialysis Technologies Limited
InventorMark Wallace
Life of this patent
Estimating the term…
Abstract
The invention relates to a dialysis machine capable of performing ultrafiltration without the need for a dedicated ultrafiltration pump. The system uses a pair of membrane flow balance pumps wherein the operation and/or the volume flow rate of the pumps can be modified during operation to bring about a net movement of dialysate either into or from the dialyser. The direction of flow of the dialysate in the dialyzer is reversible and the dialyzer can comprise two dialysate inlets, one at each end, and two dialysate outlets, one at each end.
Claims15
A dialysis machine for ultrafiltration, co p sing:
- a dialyser;
- and
- a first pump and a second pump,
- wherein:
- each pump is adapted to deliver a fresh dialysate solution to the dialyser and remove a spent dialysate solution from the dialyser,
- at least one of the first and second pumps comprising a cartridge and a platen,
- the cartridge comprising a plurality of chambers and conduits covered by a flexible membrane,
- the platen and cartridge further defining a membrane valve comprising a channel with an opening covered by the flexible membrane a valve cavity;
- a volume flow rate of the first pump is different from a volume flow rate of the second pump;
- and
- operation of at least one of the first pump and the second pump is configured to at least one of:
- remove excess fluid from the dialyser and deliver excess fluid to the dialyser,
- the dialysis machine being configured to vary the volume of the valve cavity by controlling the pressure differential across the flexible membrane of the membrane valve in order to change the shape of the flexible membrane when the membrane valve is in a closed configuration so as to effect at least one of the removal of excess fluid from the dialyser and delivery of excess fluid to the dialyser.
10 more elements
A dialysis machine for ultrafiltration comprising:
- a dialyser;
- a first pump adapted to deliver a fresh dialysate solution to the dialyser;
- and
- a second pump adapted to remove a spent dialysate solution from the dialyser;
- wherein
- at least one of the first and second pumps comprising a cartridge and a platen,
- the cartridge comprising a plurality of chambers and conduits covered by a flexible membrane,
- the platen and cartridge defining a membrane valve comprising a valve cavity and a channel with an opening covered by the flexible membrane;
- a volume flow rate of at least one of the first pump and the second pump is variable;
- the volume flow rate of at least one of the first pump and the second pump are configured to at least one of remove excess fluid from the dialyser and deliver excess fluid to the dialyser;
- and
- the dialyser being configured to vary the volume of the valve cavity, by controlling the pressure differential across the flexible membrane of the membrane valve in order to change the shape of the flexible membrane when the membrane valve is in a closed configuration.
9 more elements
A method of operating the dialysis machine for ultrafiltration comprising:
- providing a dialysis machine comprising a dialyser, a first pump, and a second pump, wherein:
- a volume flow rate of the first pump is different from a volume flow rate of the second pump;
- the first pump and the second pump each comprising a cartridge and a platen,
- the cartridge comprising a plurality of chambers and conduits covered by a flexible membrane,
- the platen and cartridge further defining a membrane valve comprising a channel with an opening covered by the flexible membrane a valve cavity;
- and
- an operation of at least one of the first pump and the second pump is configured to remove excess fluid from the dialyser and/or deliver excess fluid to the dialyser,
- for at least one of the first pump and the second pump, varying the volume of the valve cavity by controlling a pressure differential across the flexible membrane of the membrane valve in order to change the shape of the flexible membrane when the membrane valve is in a closed configuration in order to effect the removal of excess fluid from the dialyser and/or delivery of excess fluid to the dialyser.
5 more elements
A method of operating a dialysis machine for ultrafiltration comprising:
- providing a dialysis machine comprising a dialyser, a first pump adapted to deliver a fresh dialysate solution to the dialyser, and a second pump adapted to remove a spent dialysate solution from the dialyser;
- wherein:
- at least one of the first and second pumps comprising a cartridge and a platen,
- the cartridge comprising a plurality of chambers and conduits covered by a flexible membrane,
- the platen and cartridge defining a membrane valve comprising a valve cavity and a channel with an opening covered by the flexible membrane;
- a volume flow rate of at least one of the first pump and the second pump:
- is variable;
- and
- configured to at least one of remove excess fluid from the dialyser and deliver excess fluid to the dialyser;
- and
- for at least one of the first pump and the second pump;
- varying the volume of the valve cavity by controlling a pressure differential across the flexible membrane of the membrane valve in order to change the shape of the flexible membrane when the membrane valve is in a closed configuration.
9 more elements
Dependencies are inferred from the claim text.