Probes and methods of imaging a bacterial infection
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsMohammad Namavari, Gayatri Gowrishankar, Sanjiv S. Gambhir, Ananth Srinivasan
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Abstract
Embodiments of the present disclosure provide for labeled probes such as labeled maltoside probes and labeled maltotriose probes, methods of making labeled probes, pharmaceutical compositions including labeled probes, methods of using labeled probes, methods of diagnosing, localizing, monitoring, and/or assessing bacterial infections, using labeled probes, kits for diagnosing, localizing, monitoring, and/or assessing bacterial infections, using labeled probes, and the like.
Claims5
A composition comprising a labeled maltotriose probe, wherein the labeled maltotriose probe includes:
- wherein RI is a radiolabel, and wherein the radiolabel is 18F.
A method of imaging a bacterial infection in a subject comprising the steps of:
- administering to the subject a labeled maltotriose probe selected from the group consisting of:
- wherein RI is a radiolabel, and wherein the radiolabel is 18F;
- imaging at least a portion of the subject;
- and
- detecting the labeled maltotriose probe, wherein the location of the labeled maltotriose probe corresponds to the bacterial infection.
Dependencies are inferred from the claim text.