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US 10,881,734 B2Granted
Monoclonal antibodies to human fibroblast growth factor receptor 2 (HFGFR2) and methods of use thereof
AssigneeDaiichi Sankyo Company, Limited
InventorsChigusa Yoshimura, Reimi Kawaida, Kokichi Honda
Life of this patent
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Abstract
The present invention provides a pharmaceutical composition or a diagnostic composition targeting human fibroblast growth factor receptor 2 (hFGFR2).
Claims21
A monoclonal antibody or an antigen binding fragment thereof,
- wherein the monoclonal antibody consists of
- a heavy chain comprising a complimentary determining region H1 (CDRH1) consisting of the amino acid sequence represented by SEQ ID NO:
- 30, a CDRH2 consisting of the amino acid sequence represented by SEQ ID NO:
- 31, and a CDRH3 consisting of the amino acid sequence represented by SEQ ID NO:
- 32;
- and
- a light chain comprising a CDRL1 consisting of the amino acid sequence represented by SEQ ID NO:
- 33, a CDRL2 consisting of the amino acid sequence represented by SEQ ID NO:
- 34, and a CDRL3 consisting of the amino acid sequence represented by SEQ ID NO:
- 35.
7 more elements
Dependencies are inferred from the claim text.