Compositions and methods for treating and preventing proteinuria and endothelial erosion

Abstract

In some embodiments, a system and/or method may inhibit and/or ameliorate proteinuria and related comorbidities in a subject. In some embodiments, proteinuria and/or Endothelial Erosion (EE) and related comorbidities may be inhibited and/or ameliorated by maximizing a subject's serum zeta potential. A subject's serum zeta potential may be maximized by administering pharmaceutical compositions which: optimize the negative electrical surface charges of a subject's blood cells, plasma proteins, and/or endothelial surface layer; optimize the composition of a subject's bloodstream (e.g., ionic strength and ion concentrations), and/or optimize the properties of the subject's bloodstream (e.g., serum pH). In some embodiments, Proteinuria and/or EE and related comorbidities may be inhibited and/or ameliorated by: maximizing a subject's serum zeta potential; repairing damage to the endothelial surface layer in a subject; making up for a subject's urinary losses of plasma proteins; and/or optimizing blood flow and facilitating healing of damage caused by Proteinuria and/or EE.

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