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US 10,881,667 B2Granted
Method and composition for treating epilepsy
AssigneeCity University of Hong Kong
InventorsJufang He, Xiao Li, Ailian Tan, Yujie Peng, Shenghui Xu, Yujie Yang, Xu Zhang, MD. Monir Hossain
Life of this patent
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Abstract
A method of treating a subject suffering from epilepsy includes administering an effective amount of a cholecystokinin-2 receptor antagonist or a pharmaceutical acceptable salt thereof to the subject. A pharmaceutical composition includes the cholecystokinin-2 receptor antagonist or a pharmaceutical acceptable salt thereof as active ingredient, one or more antiepileptic compounds, and a pharmaceutically acceptable excipient.
Claims7
A method of treating a subject suffering from epilepsy comprising:
- administering an effective amount of a cholecystokinin-2 receptor antagonist having a structure of Formula (Ia) or a pharmaceutical acceptable salt thereof to the subject,
- wherein R1 and R2 are independently a hydrogen atom, a substituted or unsubstituted linear or branched chain C1 to C5 alkyl group, a substituted or unsubstituted aryl group, or a heteroaryl;
- and
- R3 is a hydrogen atom, a substituted or unsubstituted linear or branched chain C1 to C3 alkyl group, or a C1 to C3 alkylamino group.
1 more element
Dependencies are inferred from the claim text.