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US 10,881,637 B2Granted
Intranasal and transdermal administration of kappa-opioid-receptor agonists: salvinorin A for the treatment of neuropsychiatric and addictive disorders
OwnerAtlee Solomoninventor
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Abstract
Methods of treating neuropsychiatric disorders including affective disorders and addiction involve intranasal or transdermal administration of a substantially selective kappa-opioid-receptor agonist that is also a partial D2 agonist, such as the compound salvinorin A. Also disclosed are intranasal, transdermal and/or inhalation systems for delivering the kappa-opioid-receptor agonist.
Claims18
A method of treating tremor caused by transdermal, transnasal or inhalation administration of salvinorin A in a patient with depression, bipolar disorder or anxiety disorder, the method comprising:
- administering ketamine and/or a cannabinoid in a pharmaceutically acceptable preparation sufficient to treat the tremor.
Dependencies are inferred from the claim text.